Ming the Mechanic: Center for Collective Intelligence has some very interesting questions and discussion.
For example -
How can large groups of people produce high quality written documents?
How can groups of people make accurate predictions of future events?
How can we harness the intelligence of thousands of people around the world to help solve the problems of global climate change?
How can we create an on-line, searchable library of books from many languages and historical eras?
How can we help create commercially sustainable products and services for low-income communities around the world?